Cuyahoga
Cuyahoga is an open source .NET web site framework. It provides content management capabilities and has a modular approach. Currently it works with MS .NET 1.1 and Mono with SQL Server, PostgreSQL or MySQL as database backend.
Detailed Feature List
Node-based site structure with unlimited depth. Multiple sites with one installation. Templates with user-defined content regions. Content localization. Authorization on multiple levels (view and edit). Search engine friendly url's. Highly configurable caching for better performance (object caching for the core objects and output caching for modules). Content syndication (RSS). WYSIWYG content editor. Database independancy due to NHibernate (scripts for MS SQL Server, PostgreSQL and MySQL included). Mono support. Open Source (BSD license)