Use the COM components of Word.
Word._Application app = new Word.ApplicationClass (); app.Visible = false; object nothing = System.Reflection.Missing.Value; object temp = Environment.CurrentDirectory @ "/ resume.doc"; // document templates
Word.documents.open (Ref Nothing, Ref Nothing, Ref Nothing, Ref Nothing, Ref Nothing, Ref Nothing, Ref Nothing, Ref Nothing, Ref Nothing, Ref Nothing, Ref Nothing, Ref Nothing, Ref Nothing, REF NOTHING, REF NOTING, Ref Nothing, Ref Nothing, Ref Nothing; // Open Template
Doc.Tables [1] .cell (1, 2) .range.text = ""; // Add content to cells
// Insert the cell into the cell Doc.Tables [1] .Cell (1, 5) .Range.inlineshapes.addPicture (IMGPATH, REF NOTHING, REF NOTHING, REF NOTHING);